Most of your major mods will be in the suspension and firewall more than likely.
I know a couple of guys who have dropped old ford bodies onto first generation chevy S10 frames and have chevy running gear.
They sell a cheap and relatively easy kit for the S10 V8 conversion. After that it's pretty much just fitting the body to the frame.
What is the wheelbase on a 36? An s10 ranges from 108"-123" depending on the model.
With the s10 drop you get an updated suspension package, disc brakes, etc.