My truck has a 305 with E force supercharger. The pulley was switched to a 3" and my gauge is reading 10 psi at 5200rpm. It is a plain 305 with performer cam and Vortec 906 heads milled to make 9:1 compression. Summit headers and 3.73 and 3000 stall. It moves . The 85 mph speedometer can whip around in 10 seconds. This is my daily driver and installed the blower in july. This winter I will see how it reacts to the temp change. So far the mileage is the same as before, which is surprising for the acceleration increase.
Forced induction is, the way. Cam and displacement add up, but once you can alter the boost you enter some real fun. Cam is just moving the curve around. Power is limited by the fuel type and internal durability.
Check your driveline. Make sure you have good U joints, a trans at least upgraded TH350 quality with shift kit, and a 8.5 rear.
Pursue this dream. It is fun fun fun.