Oh my God yes you have a LOT Of testing before you pull that head off! That is one of the muthas of muthas to pull a head (I have very little mechanical experience but have pulled one of those heads before).
Don't even think of pulling that head until you have exhausted all the easy tests.
Even pulling the valve cover off you could find a broken valve spring or something. But first it's the ignition, does it get spark in that cyl?
Pull the plug (or use another) and stick it in the plug wire ground the plug and turn it over looking for a spark in the plug. No spark, there's your cause. Spark, look into the motor a little deeper.