The big issue will be that the S-10 is a considerable bit narrower in tread width than the 55. This will put your tires way in from where you would want them to sit. Some people use spacers but I can't recommend using them. If you are a fan of the wide/deep wheel look this might be a plus though.
Also the 4x4 chassis is supposed to have a tread width that is wider than the 2 wheel drive This might be something to check into, you would just have to remove all the 4x pieces.
The best thing is to get your tape measure out and do some measuring and calculating and see exactly what you are up against.
It might be noted that the first guy who is known to have put a 47/53 cab and bed on an S-10 frame narrowed and cut down the cab, hood, fenders and bed to make it fit the chassis correctly.