You'll get an answer quicker if you post the cam specs;
280 adv duration
224 dur @ 0.050
0.566 valve lift
Also posting your compression helps others with recommendations.
The carb may be a bit small,but otherwise you have a decent combo.Although big blocks respond well to bigger cams.Realistically,you might be in the 450-475 hp range.
Also,whats it going in ??