Another set of variables to consider are the weight of the vehicle, torque converter stall speed, and tire size/axle ratio.
You can put a lot more cam in the engine if its a light vehicle with high stall converter and low axle ratio (high number). I have a GMC 3/4 ton pickup (heavy) with a stock TH350, and the cam duration of 222/222 at .050 is really too much cam. It would be a lot better in a lighter vehicle or with a high stall converter. I'm looking at moving to about 206/212, or even 195/202 to get more low end torque and better gas mileage.