A automobile engine will not start with 22 degrees of initial advance.
You are confusing "initial" timing with "initial timing advance". Initial timing is when ignition occurs without any centrifugal advance..
You cannot set the initial timing when the engine is idling above 650 - 700 RPM because the centrifugal advance mechanism is advancing the initial timing. Stock production engines are the only engines that the "initial" timing can be set and only when the engine is idling below 650 - 700 RPM.
You must check with the distributor manufacturer if you want to set the initial timing when an aftermarket distributor is being used.