[F-BIRD'88]

The biggest factor will be the fuel quality you use in the tank.
You won't get far with crap pump gas in the tank.
Avoiding spark knock is all about keep the combustion pressures and temps and mixture uniformity.
The higher the mechanical compression ratio is the closer to the edge it will run.
That means that n ordder to avoid detonation you have to keep a closer eye on the engine operating
condition parameters that effect spark knock tolerance. Pressure, time, temperature, load.

Keep the engine cooling system temp in check.
Keep the spark timing in check. Proper timing curve.
Keep the air charge temp and AFR variation in check.
have the ability to detect detonation-spark knock and do something about it
eg reduce timing, reduce cylinder pressure (throttle)
change cam timing events ot adjust instantaneous cylinder pressure at that throttle load
( change the cam, move the cam)
Change the induction and or exhaust system tuning and or combine with a cam/valve event change adjustment
to a excessive cylinder pressure. ( eg choose a different intake manifold)

A method if being able to change the ignition timing on the fly ( a knob on the dash) would be nice.
A method of detecting engine spark knock, on the fly ( knock detector, driver warning device) would be nice.