Here we have separate catagories for structural elements and sheet metal repair. If the part will be carring a structural load, the bonding makers say do not use adheasive alone.
I've done several bonded panel replacements and I avoid the screws. I simply use flush head stainless pop rivets in countersunk holes and leave them in place. The glue squishes out around them when you set them and the whole thing is sealed water-tight.