You will need a double spring setup on the valves. The heads will be the weak point. They will have to be pocket ported and flowed.
Watch for coil bind, we had a good long posting on these heads a few months ago. You want to set your rev limiter 200 RPM above the shift point. DoubleVision hit most of the other tips I recommend following them.
The stock HEI starts to fall off after 4200 rpm so the upgrade like DoubleVision is highly recommended.
Luv the smell of NITRO in the morning.