I know this is a very broad question that will be specific to each application and personal preference. I have a 1969 Buick Wildcat. I just replaced the 430 with a fresh .030 over 455 upgraded oiling system. TA performance stage 1 aluminum cylinder heads, mild hydraulic roller (dosent require a stall and plenty of vaccum) TA roller rockers, Edelbrock dual plane intake with square bore or spread bore carb pad. Big tube headers and 3 inch exhaust. MSD style ignition. The car is a cruiser that will go on pretty long winded trips, I want something dependable but not sacrifice too much on the performance side if I do want to have a little fun. I'm leaning towards an Edelbrock because I've had good luck with them in the past. I've read a lot of good things about quadrajets if they are built properly. I dont have anything against Holley carb's just not familiar with them. Thanks for reading guys and looking forward to your opinions!