I am not a pro painter by any definition, and I am going to guess I am probably the least experienced person who held a spray gun, who is going to respond to this post.
Orange peel tells me the paint is too dry, and did not flow out.
Runs tell me the paint is too wet, and flowed off.
I believe the major problem is with your consistancy. With me, by far my greatest problem is consistancy with gun techniques. Is the gun perpendicular to the surface? Is the the gun the same distance to the surface, throughout the entire stroke? Is the overlap the same on each stroke? Is the gun speed the same on each stroke?
Is the paint the same visiosity each time? Is the temperature the same? Do you allow the same time for each coat to flash off, in different areas?
Notice I have not even mentioned tip sizes, air pressure, and many other variables.
Take careful notes of everything you can the next time you paint. Try to see what changes you do causes what effect. Try to be really consistant, and you should get much better results.
Trust me, I have done more than one paint application that has orange peel and runs on the same piece. It is part of the learning process. Take pride you are learning to do this yourself, and not just buying a paint job. Want to have some fun, try painting spoked wheels sometime.