Basically dome pistons are all quench area with little to no squish. Quench being the result of a small volume trapped within a large surface area, such the heat is sunk out of the volume quickly by the area. The big problem you have to check out carefully is valves missing pistons. Especially given that this style piston is usually run with big cams. Squish is a function of a zone of the chamber having a small volume such that as the piston approaches TDC mixture in the tight closing zone is ejected toward the spark plug. With a dome that's an up hill battle, pun intended.
The race with these type piston is one of power gained through compression against power lost to a convoluted burn taking place over and around the dome, and temperature being surrendred to the added surface area. Obviously well all know the compression builds power faster than the negatives take it way, you just have to appreciate that it isn't a free lunch.
You want a head that places the spark plug high to the chamber roof as that's where the mixture action is.
Certainly domed pistons have their place, but a tighter chamber, within reason, and a flat top piston is a better choice if it can be worked into the equation.
Bogie