The factory "roller" cam blocks use a cam retention plate to hold the cam in place. The nose of the "original roller cams" or "retro" as some are called today is the same style / size as any hydraulic or solid lifter cam produced since 1955.
If your block is not a factory "roller" block, then you have to run the retro. Now keep in mind that you will need run a cam button to keep the cam from walking fore and aft in its bearings. Roller cams have no taper ground into the lobes that forces the cam to the rear of the block, like the flat tappet cams do. If you use the stock timing chain cover, you may have to stiffen it up some around the area where the button contacts the underneath side. You don't want the cover to flex.
You will need the correct lifters for the block you have when running a roller cam. You will also need shorter push rods and the rocker geometry needs to be spot on for it to live. If you plan on running a double-roller timing gear set, the front of the block may need to be clearanced around the top of the cam journal boss.